Author

A. Handel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. E. Oftedal· 1 shared B. M. Kessler· 1 shared D. Howie· 1 shared D. I. Nkaleke· 1 shared E. Sezgin· 1 shared F. Bai· 1 shared G. A. Hollander· 1 shared I. A. Rota· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

B. E. Oftedal

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pre-existing Immunity to Influenza Aids Ferrets in Developing Stronger and Broader Vaccine-induced Antibody Responses

Y. Ge, Y. Lu, J. Allen, T. Einav, D. I. Nkaleke, F. Bai, A. Handel, T. Ross, Y. Shen

This study shows that pre-existing immunity in ferrets enhances vaccine-induced antibody responses, reducing the need for booster shots and broadening protection against homologous and heterologous influenza strains.

bioRxiv · Jan 31, 2024 · PreprintImmunology

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

B. E. Oftedal, S. Maio, A. Handel, M. P. White, D. Howie, S. Davis, N. Prevot, I. A. Rota, M. E. Deadman, B. M. Kessler, R. Fisher, N. S. Trede, E. Sezgin, R. M. Maizels, G. A. Hollander

This study shows that the chaperonin CCT8 is essential for T cell maturation, selection, and function by maintaining proteostasis, and its absence impairs immune protection against helminths.

bioRxiv · Aug 11, 2020Immunology