ImmunologybioRxiv
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
B. E. Oftedal, S. Maio, A. Handel…·G. A. Hollander
This study shows that the chaperonin CCT8 is essential for T cell maturation, selection, and function by maintaining proteostasis, and its absence impairs immune protection against helminths.
DOI 10.1038/s42003-021-02203-0