BiophysicsbioRxiv
A Bistable Mechanism Mediated by Integrins Controls Mechanotaxis of Leukocytes
A. Hornung, T. Sbarrato, N. Garcia-Seyda…·M.-P. Valignat
The paper shows that leukocytes use a bistable mechanism involving integrins LFA-1 and VLA-4 to decide their direction in response to flow.
DOI 10.1016/j.bpj.2019.12.013