ImmunologybioRxiv
B1a B cells require autophagy for metabolic homeostasis and self-renewal
A. J. Clarke, T. Riffelmacher, D. Braas…·A. K. Simon
This study shows B1a B cells rely on autophagy for metabolic homeostasis and self-renewal, with Atg7 deletion causing their loss due to metabolic dysregulation and mitochondrial dysfunction.
DOI 10.1084/jem.20170771