Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination With Nivolumab
K. Thudium, M. Selby, J. A. Zorn, G. Rak, X.-T. Wang, R. T. Bunch, J. M. Hogan, P. Strop, A. J. Korman
This paper characterizes relatlimab, a LAG-3-blocking antibody, showing it enhances anti-tumor activity when combined with nivolumab in preclinical models and is well-tolerated in monkeys.
bioRxiv · Jan 24, 2022Cancer Biology