Author

K. L. Black

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. S. Naqvi· 2 shared A. Thomas-Tikhonenko· 2 shared A. V. Ljubimov· 2 shared D.-T. Fuchs· 2 shared J. A. Schneider· 2 shared K. E. Hayer· 2 shared M. Koronyo-Hamaoui· 2 shared S. Y. Yang· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

A. S. Naqvi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Distinctive retinal peri-arteriolar versus peri-venular amyloid plaque distribution correlates with the cognitive performance

O. M. Dumitrascu, J. Doustar, D.-T. Fuchs, Y. Koronyo, D. S. Sherman, M. S. Miller, K. O. Johnson, R. O. Carare, S. R. Verdooner, P. D. Lyden, J. A. Schneider, K. L. Black, M. Koronyo-Hamaoui

The paper quantifies retinal perivascular amyloid plaque distribution in relation to cognitive performance, finding higher peri-arteriolar amyloid burden and correlations with cognitive decline.

bioRxiv · Feb 27, 2024Pathology

Identification of retinal tau oligomers, citrullinated tau, and other tau isoforms in early and advanced AD and relations to disease status

H. Shi, N. Mirzaei, Y. Koronyo, M. R. Davis, E. Robinson, G. M. Braun, O. Jallow, A. Rentsendorj, V. K. Ramanujan, J. Fert-Bober, A. A. Kramerov, A. V. Ljubimov, L. S. Schneider, W. G. Tourtellotte, D. Hawes, , M. Koronyo-Hamaoui

This study quantifies retinal tau isoforms in early and advanced AD and links them to brain pathology and cognitive status.

bioRxiv · Feb 13, 2024 · PreprintPathology

FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cells

S. Y. Yang, K. E. Hayer, H. Fazelinia, M. Asnani, K. L. Black, A. S. Naqvi, V. Pillai, L. A. Spruce, Y. Barash, K. S. Elenitoba-Johnson, A. Thomas-Tikhonenko

The paper identifies FBXW7β as a predominant isoform in normal and malignant pro-B cells, showing it drives a proinflammatory TNF gene cluster.

bioRxiv · Apr 24, 2022 · PreprintCell Biology

Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment

A. Galstyan, A. Chiechi, A. J. Korman, T. Sun, L. L. Isreal, O. Braubach, R. Patil, E. Shatalova, V. A. Ljubimov, J. Markman, Z. Grodzinski, K. L. Black, M. L. Penichet, E. Holler, A. V. Ljubimov, , J. Y. Ljubimova

This study develops nano immunoconjugates that cross the blood-brain barrier to activate local immune responses against gliomas, improving survival in treated mice.

bioRxiv · Nov 9, 2018 · PreprintImmunology

Aberrant splicing in B-cell acute lymphoblastic leukemia

K. L. Black, A. S. Naqvi, K. E. Hayer, S. Y. Yang, E. Gillespie, A. Bagashev, V. Pillai, S. Tasian, M. R. Gazzara, M. Carroll, D. Taylor, K. W. Lynch, Y. Barash, A. Thomas-Tikhonenko

The paper identifies widespread aberrant splicing in pediatric B-ALL, showing that splicing factor deregulation drives splicing changes and contributes to disease.

Nucleic Acids Research · Oct 24, 2018Peer-reviewedCancer Biology