R. Patil

Development and Characterization of Co-crystals Assisted with In-silico Screening for Solubility and Permeability Enhancement of Curcumin

This paper develops and characterizes co-crystals of curcumin using in-silico screening to enhance solubility and permeability, showing significant improvements in dissolution and permeability compared to pure curcumin.

Diurnal stomatal apertures profile and density ratios affect whole-canopy conductance, drought response, water-use efficiency and yield.

This study identifies dynamic stomatal traits in tomato introgression lines linked to improved drought response and yield by combining functional phenotyping with field data.

Baseline cell proliferation rates and response to UV differ in Lymphoblastoid Cell Lines derived from healthy individuals of extreme constitution types

The paper compares baseline cell proliferation rates and UV response in Lymphoblastoid Cell Lines from healthy individuals with different constitution types, finding significant differences in proliferation and recovery.

Cocculus hirsutus -derived phytopharmaceutical drug has potent anti-dengue activity

This paper identifies Cocculus hirsutus-derived AQCH as a potent anti-dengue drug with in vitro and in vivo efficacy, characterized by five chemical markers and formulated into tablets for further development.

In Vivo Monitoring of Rare Circulating Tumor Cell and Cluster Dissemination in a Multiple Myeloma Xenograft Model

This study develops a GFP-compatible DiFC method to non-invasively monitor CTC burden and detect CTC clusters in a multiple myeloma xenograft model.

In Vivo Flow Cytometry of Extremely Rare Circulating Cells

This paper introduces a new technique called Diffuse in vivo Flow Cytometry (DiFC) for detecting rare fluorescently-labeled circulating cells in mice without drawing blood, achieving high accuracy and speed.

Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment

This study develops nano immunoconjugates that cross the blood-brain barrier to activate local immune responses against gliomas, improving survival in treated mice.