Author

A. Japaridze

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4 Biophysics· 3 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:chromatin & epigenetic regulation· 5 Organism:bacteria (other)· 4 Organism:E. coli· 4 Assay:imaging· 4 Research Focus:cell type annotation· 3 Approach:microscopy & imaging analysis· 3 Assay:DNA methylation· 2

Frequent Co-Authors

C. Dekker· 9 shared F. Alijani· 3 shared I. Roslon· 3 shared J. W. J. Kerssemakers· 3 shared P. Steeneken· 3 shared C. Gogou· 2 shared A. Birnie· 1 shared A. van Belkum· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

9 shared papersMicrobiology

C. Dekker

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Prospects and Challenges for Graphene Drums As Sensors Of Individual Bacteria

I. Roslon, A. Japaridze, L.-V. Naarden, L. Smeets, C. Dekker, A. van Belkum, P. Steeneken, F. Alijani

This paper discusses the potential of graphene drums as nanomotion sensors for studying microbial processes at the single-cell level and explores their future applications in clinical settings.

bioRxiv · Nov 20, 2023Microbiology

Microwell-enhanced optical rapid antibiotic susceptibility testing of single bacteria

I. Roslon, A. Japaridze, S. Rodenhuis, L. Hamoen, M. Ghatkesar, P. Steeneken, C. Dekker, F. Alijani

This paper introduces an optical method to rapidly assess antibiotic susceptibility of single bacteria within one hour by analyzing light intensity fluctuations.

iScience · Nov 1, 2023Peer-reviewedBioengineering

Direct observation of a crescent-shape chromosome in Bacillus subtilis

M. Tisma, F. P. Bock, J. Kerssemakers, A. Japaridze, S. Gruber, C. Dekker

The paper visualizes the crescent shape of the Bacillus subtilis chromosome in live cells and identifies key proteins involved in its structure.

bioRxiv · Feb 9, 2023Microbiology

MukBEF-dependent chromosomal organization in widened Escherichia coli

A. Japaridze, R. van Wee, C. Gogou, J. W. J. Kerssemakers, C. Dekker

This study investigates the role of MukBEF in E. coli chromosome organization, showing its ATP-dependent translocation and non-uniform distribution, and its importance for sister chromosome decatenation.

bioRxiv · Jul 13, 2022Microbiology

Extracting and characterizing protein-free megabasepair DNA for in vitro experiments

M. Holub, A. Birnie, A. Japaridze, J. van der Torre, M. den Ridder, C. de Ram, M. Pabst, C. Dekker

The paper presents a method to isolate megabasepair-long deproteinated DNA for in vitro studies, enabling the investigation of chromosome organization using long DNA substrates.

bioRxiv · Jun 22, 2022 · PreprintBiophysics

Probing nanomotion of single bacteria with graphene drums

I. Roslon, A. Japaridze, P. Steeneken, C. Dekker, F. Alijani

This study measures nanomotion of single E. coli cells using graphene drums, identifies flagella as the source, and demonstrates single-cell antibiotic susceptibility testing.

bioRxiv · Sep 21, 2021Biophysics

DNA sequence-directed cooperation between nucleoid-associated proteins

A. Japaridze, W. Yang, C. Dekker, W. Nasser, G. Muskhelishvili

The paper investigates how DNA sequence arrangements influence the structural organization of nucleoprotein complexes formed by FIS and H-NS in bacteria.

bioRxiv · Jun 14, 2020Biophysics

Direct observation of independently moving replisomes in Escherichia coli

A. Japaridze, C. Gogou, J. W. J. Kerssemakers, H. M. Nguyen, C. Dekker

The paper observes independently moving replisomes in E. coli, supporting the train-track model over the factory model for chromosome replication.

bioRxiv · Aug 13, 2019Cell Biology

Direct Imaging of the circular chromosome of a live bacterium

F. Wu, A. Japaridze, X. Zheng, J. W. J. Kerssemakers, C. Dekker

This study directly images the circular chromosome of live E. coli cells, revealing its torus topology and dynamic structural features.

Nature Communications · May 16, 2019Peer-reviewedMicrobiology