Author

W. Nasser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 5 Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 4 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Approach:mechanistic / dynamical model· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

S. Reverchon· 6 shared S. Meyer· 5 shared R. Forquet· 4 shared F. Hommais· 3 shared A. Altshuler· 2 shared G. Muskhelishvili· 2 shared R. Shalom-Feuerstein· 2 shared S. Bhattacharya· 2 shared

Activity by Year

2019-2021 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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6 shared papersMicrobiology

S. Reverchon

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Biomechanical property of limbal niche maintains stemness through YAP

S. Bhattacharya, A. Mukherjee, S. Pisano, S. Dimri, E. Knaane, A. Altshuler, W. Nasser, S. Dey, L. Shi, I. Mizrahi, O. Jokel, A. Amitai-Lange, A. Kaganovsky, M. Mimouni, S. Socea, , R. Shalom-Feuerstein

This study shows that biomechanical properties of the limbal niche regulate YAP activity, which is essential for maintaining stemness and regeneration in corneal epithelial stem cells.

bioRxiv · May 25, 2021Cell Biology

RNA chaperones Hfq and ProQ play a key role in the virulence of the plant pathogenic bacterium Dickeya dadantii

S. Leonard, C. Villard, W. Nasser, S. Reverchon, F. Hommais

This study shows that RNA chaperones Hfq and ProQ regulate virulence in Dickeya dadantii by affecting mRNA levels of virulence factors.

bioRxiv · Mar 26, 2021Microbiology

The discriminator sequence is a primary determinant in the supercoiling response of bacterial promoters

R. Forquet, M. Pineau, W. Nasser, S. Reverchon, S. Meyer

The paper identifies the discriminator sequence as a key determinant of bacterial promoter supercoiling response, validated through in vitro, in vivo, and evolutionary analyses.

bioRxiv · Oct 1, 2020 · PreprintMicrobiology

Mapping the complex transcriptional landscape of the phytopathogenic bacterium Dickeya dadantii

R. Forquet, X. Jiang, W. Nasser, F. Hommais, S. Reverchon, S. Meyer

This study maps the transcriptional landscape of Dickeya dadantii using multiple transcriptomic datasets, revealing complex transcription units and regulatory features beyond traditional operons.

bioRxiv · Sep 30, 2020Microbiology

The nucleoid-associated protein IHF acts as a domainin protein coordinating the bacterial virulence traits with global transcription

S. Reverchon, S. Meyer, R. Forquet, F. Hommais, G. Muskhelishvili, w. Nasser

This study shows that IHF coordinates bacterial virulence traits with global transcription by altering DNA topology and gene expression in Dickeya dadantii.

bioRxiv · Aug 24, 2020Microbiology

Development and validation of an HPLC method to quantify 2-Keto-3-deoxy-gluconate (KDG), a major metabolite in pectin and alginate degradation pathways

S. Martis B, M. Droux, F. Deboudard, W. Nasser, S. Meyer, S. Reverchon

The paper develops and validates an HPLC method with fluorescence detection to quantify KDG, a metabolite from pectin and alginate degradation pathways.

bioRxiv · Jul 24, 2020Biochemistry

Capturing limbal epithelial stem cell population dynamics, signature and their niche

A. Altshuler, A. Amitai Lange, N. Tarazi, S. Dey, L. Strinkovsky, S. Bhattacharya, S. Hadad-Porat, W. Nasser, J. Imeri, G. Ben-David, B. Tiosano, E. Berkowitz, N. Karin, Y. Savir, R. Shalom-Feuerstein

This study identifies two distinct limbal stem cell populations with different proliferation rates and regulatory mechanisms in mice.

bioRxiv · Jun 30, 2020 · PreprintCell Biology

DNA sequence-directed cooperation between nucleoid-associated proteins

A. Japaridze, W. Yang, C. Dekker, W. Nasser, G. Muskhelishvili

The paper investigates how DNA sequence arrangements influence the structural organization of nucleoprotein complexes formed by FIS and H-NS in bacteria.

bioRxiv · Jun 14, 2020Biophysics

Bacterial genome architecture shapes global transcriptional regulation by DNA supercoiling

B. El Houdaigui, R. Forquet, T. Hindre, D. Schneider, W. Nasser, S. Reverchon, S. Meyer

The paper models how DNA supercoiling affects transcription in bacteria and shows that global gene orientation influences supercoiling sensitivity.

bioRxiv · Feb 27, 2019Microbiology