Profiling extracellular vesicles in circulation enables the early detection of ovarian cancer
H. Lee, D. M. Dinulescu, C. M. Castro, A. Jo, A. Green, J. E. Medina, S. Iyer, A. W. Ohman, E. T. McCarthy, F. Reinhardt, T. Gerton, D. Demehin, R. Mishra, D. L. Kolin, H. Zheng, , B. R. Reuda
This study develops an extracellular vesicle-based test to detect early-stage high-grade serous ovarian cancer with high sensitivity and specificity using markers identified from murine models and validated in a human pilot study.
bioRxiv · Jan 19, 2023 · PreprintCancer Biology