Author

K.-M. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

S. S. Yoon· 3 shared J. Kim· 2 shared K. B. Min· 2 shared Y. Park· 2 shared A. B. Hanker· 1 shared A. F. Carisey· 1 shared A. G. York· 1 shared A. Jo· 1 shared

Activity by Year

2020-2022 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersMicrobiology

S. S. Yoon

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

CD244 regulates both innate and adaptive immune axes in melanoma by inhibiting autophagy-mediated M1 macrophage maturation

J. Kim, T.-J. Kim, S. Chae, S. Park, H. Ha, Y. Park, C. J. Yoon, J. Kim, J. Kim, K. Im, H. Lee, K. Lee, J. Kim, D. Kim, E. Lee, , K.-M. Lee

This study shows CD244 inhibits macrophage maturation in melanoma, enhancing T cell responses and improving tumor rejection when combined with PD-L1 blockade.

bioRxiv · Dec 1, 2022 · PreprintImmunology

Chemical Inhibitors of DksA1, a Conserved Bacterial Transcriptional Regulator, Suppressed Quorum Sensing-Mediated Virulence in Pseudomonas aeruginosa

K. B. Min, W. T. Hwang, K.-M. Lee, S. S. Yoon

This study identifies two chemical inhibitors of DksA1 that suppress quorum sensing-mediated virulence in Pseudomonas aeruginosa, reducing virulence factors and increasing antibiotic susceptibility.

bioRxiv · Dec 10, 2020Microbiology

A Robust Genome-Wide Association Study Uncovers Signature Genetic Alterations among Pseudomonas aeruginosa Cystic Fibrosis Isolates

W. Hwang, J. H. Yong, K. B. Min, K.-M. Lee, S. S. Yoon

This study performs a genome-wide association study on Pseudomonas aeruginosa isolates from cystic fibrosis patients and identifies genetic alterations specific to these isolates.

bioRxiv · Dec 2, 2020Microbiology

The SARS-CoV-2 RNA interactome

S. Lee, Y.-s. Lee, Y. Choi, A. Son, Y. Park, K.-M. Lee, J. Kim, J.-S. Kim, V. N. Kim

This study identifies 109 host factors interacting with SARS-CoV-2 RNA and reveals their roles in antiviral or proviral functions through RNP capture and knockdown experiments.

bioRxiv · Nov 2, 2020Microbiology

Nasal commensal, Staphylococcus epidermidis shapes the mucosal environment to prevent influenza virus invasion through Serpine1 induction

A. Jo, J. Won, C. H. Gil, J. Y. Choi, K.-M. Lee, S. S. Yoon, H. J. Kim

This paper shows that Staphylococcus epidermidis in the nasal mucosa induces Serpine1, which blocks influenza virus invasion by inhibiting protease activity and IFN-λ signaling.

bioRxiv · Aug 3, 2020 · PreprintImmunology

A Versatile Oblique Plane Microscope for Large-Scale and High-Resolution Imaging of Subcellular Dynamics.

E. Sapoznik, B.-J. Chang, J. Huh, R. J. Ju, E. Azarova, T. Pohlkamp, E. S. Welf, D. Broadbent, A. F. Carisey, S. J. Stehbens, K.-m. Lee, A. Marin, A. B. Hanker, J. C. Schmidt, C. L. Arteaga, , R. P. Fiolka

This paper introduces an improved oblique plane microscope with enhanced resolution and usability, demonstrating its application in imaging various subcellular dynamics and challenging biological phenomena.

bioRxiv · Apr 7, 2020Biophysics

Induced copy-back RNA synthesis as a novel therapeutic mechanism against RNA viruses

R. Janissen, A. Woodman, K.-M. Lee, I. Moustafa, F. Fitzgerald, P.-N. Huang, L. Kuijpers, A. L. Perkins, D. A. Harki, J. J. Arnold, B. Solano, S.-R. Shih, C. E. Cameron, N. H. Dekker

This study shows that a ribonucleotide analogue induces copy-back RNA synthesis, a new mechanism to combat RNA viruses by promoting defective viral genomes.

bioRxiv · Feb 12, 2020 · PreprintMicrobiology