Author

A. Jorgensen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1 Pathology· 1 Pharmacology & Toxicology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:clinical cohort / trial· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Alfirevic· 1 shared A. G. Jurik· 1 shared A. Marson· 1 shared B. P. Koeleman· 1 shared C. A. B. Svane· 1 shared C. Campbell· 1 shared C. Depondt· 1 shared C. Leu· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Alfirevic

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Exploring the functional, protective, and transcriptomic effects of GIP on cytokine-exposed human pancreatic islets and EndoC-βH5 cells

K. Henriksen, A. Jorgensen, S. Kaur, R. Gerwig, C. A. B. Svane, F. K. Knop, J. Storling

This study investigates the functional, protective, and transcriptomic effects of GIP on cytokine-exposed human pancreatic islets and EndoC-βH5 cells, finding CaMK2-dependent insulinotropic effects but limited cytoprotection and transcriptomic modulation.

bioRxiv · Jun 17, 2024Cell Biology

Role of transporters and enzymes in metabolism and distribution of 4-chlorokynurenine and metabolites

W. Patel, R. G. Shankar, M. A. Smith, H. R. Snodgrass, M. Pirmohamed, A. Jorgensen, A. Alfirevic, D. Dickens

The paper investigates the metabolism and distribution of 4-chlorokynurenine and its metabolites, identifying a novel acetylated metabolite and pharmacogenetic associations affecting drug levels and transporter interactions.

bioRxiv · Jul 14, 2023 · PreprintPharmacology & Toxicology

Polygenic risk score analysis reveals shared genetic burden between epilepsy and psychiatric comorbidities

C. Campbell, D. Lewis-Smith, C. Leu, H. Martins, S. Wolking, R. Krause, T. J. O'Brien, G. Sills, F. Zara, B. P. Koeleman, C. Depondt, A. Marson, H. Stefansson, K. Stefansson, J. Craig, , G. Cavalleri

This study uses polygenic risk scores to show that people with epilepsy have increased genetic risk for depression, psychosis, and ADHD, with stronger associations in drug-resistant cases.

medRxiv · Jul 4, 2023 · PreprintGenetic & Genomic Medicine

Germaphobia! Does our Relationship with, and Knowledge of Biodiversity Affect our Attitudes Towards Microbes?

J. M. Robinson, R. Cameron, A. Jorgensen

This study examines how knowledge of biodiversity and attitudes towards microbes relate to germaphobia, finding that nature engagement and microbial literacy correlate with more positive attitudes towards microbes.

bioRxiv · Feb 8, 2021Scientific Communication & Education

Radiographic and clinical risk factors of total knee arthroplasty in asymptomatic knees; a 15-year follow-up study

F. K. Nielsen, A. G. Jurik, A. Jorgensen, N. Egund

This study identifies radiographic and clinical factors associated with the risk of total knee arthroplasty in asymptomatic knees with contralateral symptomatic OA over 15 years.

bioRxiv · Oct 23, 2019 · PreprintPathology