Pharmacology & ToxicologybioRxivPreprint
Tackling emerging artemisinin resistance by modulating the defensive oxido-reductive mechanism of human malaria parasite by repurposing nitrofurantoin
S. Shafi, S. Gupta, R. Jain…·S. Singh
This paper evaluates the anti-malarial potential of Nitrofurantoin against sensitive and resistant Plasmodium falciparum strains, finding synergistic effects with artemisinin and enhanced oxidative stress.
DOI 10.1101/2023.04.18.537303