BioengineeringbioRxiv
Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control
B. Mahata, A. Cabrera, D. A. Brenner…·I. B. Hilton
This paper develops compact human mechanosensitive TADs for synthetic transcriptional control, showing they are potent, versatile, and well-tolerated in primary cells.
DOI 10.1038/s41592-023-02036-1