Author

A. Lacour

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. E. K. E. Kiib· 1 shared A. Hirsch· 1 shared A. K. H. Hirsch· 1 shared C. Chen· 1 shared D. Aguilar· 1 shared D. J. Walsh· 1 shared D. Olagnier· 1 shared E. Diamanti· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. E. K. E. Kiib

Mutual co-authors in cluster

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2 papers

Recent·Most cited

IspE Kinase as an Anti-infective Target: Role of a Hydrophobic Pocket in Inhibitor Binding

R. Hamid, D. J. Walsh, A. Lacour, E. Diamanti, D. Aguilar, M. M. Hamed, A. K. H. Hirsch

The paper investigates IspE kinase homologs from pathogenic bacteria, identifies structural differences affecting inhibitor binding, and highlights a hydrophobic pocket critical for inhibitor specificity in Acinetobacter baumannii.

bioRxiv · Jun 17, 2024Biophysics

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

F. H. Waqas, M. Shehata, W. A. M. Elgaher, A. Lacour, N. Kurmasheva, F. Begnini, A. E. K. E. Kiib, J. Dahlmann, C. Chen, T. B. Poulsen, S. Merkert, U. Martin, R. Olmer, D. Olagnier, A. Hirsch, , F. Pessler

This paper shows NRF2 activators inhibit influenza A virus by blocking nuclear export of viral RNPs, independent of NRF2 signaling, through interaction with XPO1 and KEAP1.

bioRxiv · Jun 11, 2023Microbiology