Author

M. Shehata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Pleschka· 2 shared A. E. K. E. Kiib· 1 shared A. Hirsch· 1 shared A. L. Tse· 1 shared A. Lacour· 1 shared A. Ojha· 1 shared A. Venkitaraman· 1 shared A. Wang· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

S. Pleschka

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens

X. Nuqui, L. Casalino, L. Zhou, M. Shehata, A. Wang, A. L. Tse, A. Ojha, F. L. Kearns, M. A. Rosenfeld, E. H. Miller, C. M. Acreman, S.-H. Ahn, K. Chandran, J. S. McLellan, R. E. Amaro

This study designs stabilized SARS-CoV-2 S2 immunogens using simulation-driven approaches, showing improved stability and immunogenicity.

bioRxiv · Oct 24, 2023Biophysics

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

F. H. Waqas, M. Shehata, W. A. M. Elgaher, A. Lacour, N. Kurmasheva, F. Begnini, A. E. K. E. Kiib, J. Dahlmann, C. Chen, T. B. Poulsen, S. Merkert, U. Martin, R. Olmer, D. Olagnier, A. Hirsch, , F. Pessler

This paper shows NRF2 activators inhibit influenza A virus by blocking nuclear export of viral RNPs, independent of NRF2 signaling, through interaction with XPO1 and KEAP1.

bioRxiv · Jun 11, 2023Microbiology

A transcriptional response to replication stress selectively expands a subset of BRCA2-mutant mammary epithelial cells

M. Ghaderi Najafabadi, G. K. Gray, L. R. Kong, K. Gupta, D. Perera, J. S. Brugge, A. Venkitaraman, M. Shehata

The paper shows that BRCA2-mutant mammary epithelial cells with low hormone receptor expression expand under replication stress through a transcriptional response involving Tspan8 and Thrsp.

bioRxiv · Nov 14, 2022 · PreprintCancer Biology

Broad antiviral effects of Echinacea purpurea against SARS-CoV-2 variants of concern and potential mechanism of action

S. Vimalanathan, M. Shehata, K. Sadasivam, S. Delbue, M. Dolci, E. Pariani, S. D'Alessandro, S. Pleschka

This study evaluates the antiviral effects of Echinacea purpurea against SARS-CoV-2 variants and identifies potential mechanisms of action through molecular dynamics analysis.

Microorganisms · Oct 29, 2022Peer-reviewedMicrobiology