Author

F. Pessler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

F. Chen· 2 shared S. Pleschka· 2 shared A. E. K. E. Kiib· 1 shared A. Hirsch· 1 shared A. Iqbal· 1 shared A. Lacour· 1 shared A. Michelucci· 1 shared A. Mostafa· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

F. Chen

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

F. H. Waqas, M. Shehata, W. A. M. Elgaher, A. Lacour, N. Kurmasheva, F. Begnini, A. E. K. E. Kiib, J. Dahlmann, C. Chen, T. B. Poulsen, S. Merkert, U. Martin, R. Olmer, D. Olagnier, A. Hirsch, , F. Pessler

This paper shows NRF2 activators inhibit influenza A virus by blocking nuclear export of viral RNPs, independent of NRF2 signaling, through interaction with XPO1 and KEAP1.

bioRxiv · Jun 11, 2023Microbiology

Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection

A. Sohail, A. Iqbal, N. Sahini, M. Tantawy, M. Winterhoff, R. Geffers, T. Ebensen, K. Schughart, M. Pils, F. Chen, C. A. Guzman, M. Preusse, S. Pleschka, A. Mostafa, C. Falk, , F. Pessler

This study shows itaconate and its derivatives reduce interferon responses and inflammation in influenza A virus infection without increasing viral replication.

bioRxiv · Jan 20, 2021Immunology

Human IFITM3 restricts Chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction

S. Franz, T. Zillinger, F. Pott, C. Schüler, S. Dapa, C. Fischer, V. Passos, S. Stenzel, F. Chen, K. Döhner, G. Hartmann, B. Sodeik, F. Pessler, G. Simmons, J. F. Drexler, C. Goffinet

This study shows IFITM3 restricts CHIKV and MAYV infection and is counteracted by these viruses, with a variant showing similar antiviral activity to wild-type.

bioRxiv · Sep 11, 2020Microbiology