B cell alpha(v) integrin regulates tissue specialization and clonal expansion of lung germinal center and memory B cells after viral infection.
A. Montiel-Armendariz, K. Roe, J. Lagos-Orellana, L. V. Martinez-Castro, M. J. Dufort, O. J. Harrison, A. Lacy-Hulbert, M. Acharya
This study shows that B cell v integrin limits GC activity and memory B cell expansion in the lung after IAV infection, suggesting it as a target for improving mucosal vaccines.
bioRxiv · Apr 3, 2024Immunology