Author

A. Lappala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:Hi-C· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Research Focus:spatial domain detection· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Kriz· 1 shared B. McMahon· 1 shared C.-S. Tung· 1 shared C.-Y. Wang· 1 shared H. Michalk· 1 shared J. Lee· 1 shared J. Miner· 1 shared K. Sanbonmatsu· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Kriz

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2 papers

Recent·Most cited

4D chromosome reconstruction elucidates the spatial reorganization of the mammalian X-chromosome

A. Lappala, C.-Y. Wang, A. Kriz, H. Michalk, K. Tan, J. Lee, K. Sanbonmatsu

The paper uses 4DHiC to reconstruct 3D chromosome dynamics, showing X-chromosome reorganization during inactivation involves persistent smaller structures and Xist RNA diffusion.

bioRxiv · Jan 21, 2021 · PreprintBiophysics

Structural transition and antibody binding of Ebola GP and Zika E proteins from pre-fusion to fusion-initiation state

A. Lappala, W. Nishima, J. Miner, P. Fenimore, W. Fischer, P. Hraber, M. Zhang, B. McMahon, C.-S. Tung

The paper models the fusion initiation state structures of Ebola GP and Zika E proteins using computational approaches, enhancing understanding of neutralizing antibodies.

bioRxiv · Mar 20, 2018Biophysics