Desmin is a modifier of dystrophic muscle features in Mdx mice
A. Ferry, J. Messeant, A. Parlakian, M. Lemaitre, P. Roy, C. Delacroix, A. Lilienbaum, Y. Hovhannisyan, D. Furling, A. F. Klein, Z. Li, O. Agbulut
This study shows that desmin deletion in Mdx mice worsens muscle weakness, fragility, and fatigue resistance, while desmin gene transfer improves these features.
bioRxiv · Aug 23, 2019 · PreprintPathology