Author

A. Lyon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:yeast· 1

Frequent Co-Authors

A. F. Brilot· 1 shared A. F. Selvia· 1 shared A. Maxwell· 1 shared A. Sali· 1 shared A. T. Marti· 1 shared A. Zelter· 1 shared D. A. Agard· 1 shared E. E. Garland-Kuntz· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. F. Brilot

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2 papers

Recent·Most cited

CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation

A. F. Brilot, A. Lyon, A. Zelter, S. Viswanath, A. Maxwell, M. J. MacCoss, E. G. Muller, A. Sali, T. N. Davis, D. A. Agard

This study elucidates the role of the CM1 motif in Spc110p in facilitating γ-Tubulin Small Complex (γTuSC) assembly and γ-Tubulin Ring Complex (γTuRC) formation in yeast.

bioRxiv · Nov 21, 2020Biochemistry

Functional and structural characterization of allosteric activation of Phospholipase Cϵ by Rap1A

M. Sieng, A. F. Selvia, E. E. Garland-Kuntz, J. B. Hopkins, I. J. Fisher, A. T. Marti, A. Lyon

This study shows Rap1A allosterically activates PLCε by stabilizing interactions between the RA2 domain and the PLC core, confirmed through biochemical and structural analyses.

bioRxiv · Jul 10, 2020Biochemistry