A. Zelter

The kinesin motor Kif9 regulates centriolar satellite positioning and mitotic progression.

This study shows that Kif9 regulates centriolar satellite positioning and mitotic progression by affecting centrosome maturation and proteostasis.

BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation.

This study identifies intrinsically disordered regions in BRCA1/BARD1 that mediate chromatin recruitment and ubiquitylation, enhancing DNA damage repair and transcriptional regulation.

Discovery and visualization of uncharacterized drug-protein adducts using mass spectrometry.

The paper introduces Magnum, an algorithm for identifying drug-protein adducts, and Limelight, a tool for analyzing and visualizing adduct data, validated with CYP3A4 examples.

CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation

This study elucidates the role of the CM1 motif in Spc110p in facilitating γ-Tubulin Small Complex (γTuSC) assembly and γ-Tubulin Ring Complex (γTuRC) formation in yeast.

A Stu2-mediated intrinsic tension-sensing pathway promotes chromosome biorientation in vivo

This study identifies a Stu2-mediated tension-sensing pathway that works with Aurora B to correct kinetochore attachments in vivo.

Novel phosphorylation states of the yeast spindle pole body

The paper reports a phosphoproteomic analysis of yeast spindle pole bodies (SPBs) under two cell cycle conditions, identifying novel phosphorylation sites on γ-TuSC that regulate microtubule nucleation and spindle length.

The human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore-microtubule attachments

This study shows the Ska complex directly strengthens kinetochore-microtubule attachments by forming a load-bearing connection with the Ndc80 complex and microtubule tips.