Author

A. M. Vrieze

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Aktar· 1 shared A. Lac· 1 shared B. H. Dickson· 1 shared B. Heit· 1 shared C. Fink· 1 shared C. Jung· 1 shared E. N. Blythe· 1 shared G. A. Dekaban· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Aktar

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintFeb 10, 2023

SARS-CoV-2 NSP5 Antagonizes MHC II Expression by Subverting Histone Deacetylase 2

N. Taefehshokr, A. Lac, A. M. Vrieze…·B. Heit

This paper identifies how SARS-CoV-2 NSP5 suppresses MHC II expression by delivering HDAC2 to IRF3 at the CIITA promoter, leading to reduced CIITA and MHC II levels.

DOI 10.1101/2023.02.10.528032

humanbulk RNA-seq

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