Hexosamine pathway activation improves memory but does not extend lifespan in mice.
K. Allmeroth, M. D. Hartman, M. Purrio, A. Mesaros, M. S. Denzel
This study examines the effects of hexosamine pathway activation in mice through dietary supplementation and genetic manipulation, finding improved memory but no lifespan extension.
bioRxiv · Jan 7, 2022Physiology