Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism
A. J. Alfaro Nunez, C. Dittner, J. Becker, A. Loft, A. Mhamane, A. Maida, A. Georgiadi, P. Tsokanos, K. Klepac, E. Molocea, R. Merahbi, K. Motzler, J. Geppert, R. Karikari, J. Szendroedi, , S. Herzig
This study shows that SUMOylation of Prox1 regulates hepatic cholesterol metabolism in response to fasting, with implications for metabolic health.
bioRxiv · Aug 17, 2022Physiology