Author

G. Wolff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

A. J. Koster· 3 shared M. Barcena· 3 shared S. Zheng· 3 shared A. Fischer· 2 shared D. Agard· 2 shared E. J. Snijder· 2 shared J. Rodriguez-Vita· 2 shared L. Wiedmann· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

A. J. Koster

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

AreTomo: An integrated software package for automated marker-free, motion-corrected cryo-electron tomographic alignment and reconstruction

S. Zheng, G. Wolff, G. Greenan, Z. Chen, F. G. A. Faas, M. Barcena, A. J. Koster, Y. Cheng, D. Agard

AreTomo automates motion-corrected cryo-electron tomographic alignment and reconstruction, enabling high-resolution subtomogram averaging and real-time feedback during data collection.

bioRxiv · Feb 15, 2022Cell Biology

Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function

G. Wolff, M. Sakurai, A. Mhamane, A. Maida, I. K. Deligiannis, K. Yin, P. Weber, A. Weider, M. Troullinaki, A. Zeigerer, M. Roden, N. Volk, T. Poth, T. Hackert, L. Wiedmann, , S. Herzig

This study shows that deleting TSC22D4 in hepatocytes reduces liver damage in NASH by improving mitochondrial function and lipid metabolism.

bioRxiv · Dec 17, 2021Physiology

Semaphorin 3C exacerbates liver fibrosis

F. De Angelis Rigotti, L. Wiedmann, M. O. Hubert, M. Vacca, S. S. Hasan, I. Moll, S. Carvajal, W. Jimenez, M. Starostecka, A. T. Billeter, B. Müller-Stich, G. Wolff, B. Ekim-Üstünel, S. Herzig, C. Mogler, , J. Rodriguez-Vita

This study identifies SEMA3C as a key driver of liver fibrosis by enhancing TGF-β signaling in hepatic stellate cells.

bioRxiv · Jul 29, 2021Pathology

A molecular pore spans the double membrane of the coronavirus replication organelle

G. Wolff, R. W. A. L. Limpens, J. C. Zevenhoven-Dobbe, U. Laugks, S. Zheng, A. W. M. de Jong, R. I. Koning, D. A. Agard, K. Grünewald, A. J. Koster, E. J. Snijder, M. Barcena

The paper identifies a molecular pore in coronavirus replication organelles that facilitates RNA export to the cytosol, suggesting it as a potential drug target.

bioRxiv · Jun 25, 2020Microbiology

Mind the gap: micro-expansion joints drastically decrease the bending of FIB-milled cryo-lamellae

G. Wolff, R. W. A. L. Limpens, S. Zheng, E. J. Snijder, D. Agard, A. J. Koster, M. Barcena

This paper introduces micro-expansion joints to reduce lamella bending during cryo-FIB-milling, improving structural studies of biological samples.

bioRxiv · May 31, 2019Microbiology