BiochemistrybioRxiv
Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan
M. J. Anderson, A. N. Hayward, A. T. Smiley…·W. R. Gordon
This study identifies a unique mechanism by which dystroglycan is cleaved by MMPs, showing that structural changes disrupt DGC integrity and contribute to disease.
DOI 10.1016/j.str.2024.08.019