Author

A. N. Holding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. E. Cullen· 3 shared F. Markowetz· 3 shared F. M. Giorgi· 2 shared A. Donnelly· 1 shared A. Godicelj· 1 shared A. Sawle· 1 shared J. Stenning· 1 shared K. Kishore· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

A. E. Cullen

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3 papers

Recent·Most cited

Cancer BiologybioRxivJan 17, 2023

In Breast Cancer ZMIZ1 Co-Regulates E2F2 as Part of the Estrogen Receptor-Mediated Cell-Cycle Response

W. Zhao, S. F. Rose, R. Blake…·A. N. Holding

This study identifies ZMIZ1 as a co-regulator of E2F2 in the estrogen receptor-mediated cell-cycle response in breast cancer, showing its role in tumor proliferation and patient prognosis.

DOI 10.1530/jme-23-0133

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivApr 21, 2019

VULCAN integrates ChIP-seq with patient-derived co expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

A. N. Holding, F. M. Giorgi, A. Donnelly…·F. Markowetz

DOI 10.1186/s13059-019-1698-z

humanChIP-seq

𝕏 PostBluesky

Cancer BiologybioRxivAug 23, 2018

Genome-wide Estrogen Receptor-alpha activation is sustained, not cyclical

A. N. Holding, A. E. Cullen, F. Markowetz

This study shows that estrogen receptor-alpha binding is sustained, not cyclical, using genome-wide analysis with multiple replicates and a new method.

DOI 10.7554/elife.40854

humanChIP-seq

𝕏 PostBluesky