Author

A. Sawle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. E. Cullen· 1 shared A. Godicelj· 1 shared A. Hoyle· 1 shared A. Liston· 1 shared A. M. Piskorz· 1 shared A. N. Holding· 1 shared A. N. J. McKenzie· 1 shared A.-M. Mes-Masson· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. E. Cullen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tissue-resident regulatory T cells exert dualistic anti-tumour and pro-repair function in the exocrine pancreas

J. Stockis, T. Yip, S. Raghunathan, C. Garcia, S. Lee, C. Simpson, S. Silvain, M. J. Schuijs, J. Araos, S. Png, G. Raddi, O. Bricard, T. Y. So, S. Mack, P. Papadopoulos, , T. Y. F. Halim

This study identifies a rare pancreatic tissue-resident regulatory T cell population that exhibits both anti-tumour and pro-repair functions in the exocrine pancreas.

bioRxiv · Feb 15, 2024 · PreprintImmunology

An ancient gene regulatory network sets the position of the forebrain in chordates

G. Gattoni, D. Keitley, A. Sawle, E. Benito Gutierrez

The paper identifies a conserved gene regulatory network in deuterostomes that positions the forebrain and links it to the evolution of apical organs.

bioRxiv · Mar 13, 2023Evolutionary Biology

In Breast Cancer ZMIZ1 Co-Regulates E2F2 as Part of the Estrogen Receptor-Mediated Cell-Cycle Response

W. Zhao, S. F. Rose, R. Blake, A. Godicelj, A. E. Cullen, J. Stenning, L. Beevors, M. Gehrung, S. Kumar, K. Kishore, A. Sawle, M. Eldridge, F. M. Giorgi, K. S. Bridge, F. Markowetz, A. N. Holding

This study identifies ZMIZ1 as a co-regulator of E2F2 in the estrogen receptor-mediated cell-cycle response in breast cancer, showing its role in tumor proliferation and patient prognosis.

bioRxiv · Jan 17, 2023Cancer Biology

Molecular landscape and functional characterization of centrosome amplification in ovarian cancer

C. M. Sauer, J. A. Hall, D.-L. Couturier, T. Bradley, A. M. Piskorz, J. Griffiths, A. Sawle, M. D. Eldridge, P. Smith, K. Hosking, M. A. Reinius, L. Morrill Gavarro, A.-M. Mes-Masson, D. Ennis, D. Millan, , J. D. Brenton

This study identifies centrosome amplification as a common and heterogeneous feature in HGSOC, linked to CIN and treatment resistance.

bioRxiv · Sep 13, 2022Cancer Biology