Author

A. N. Kousholt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

J. Jonkers· 2 shared A. A. Sartori· 1 shared A. Duarte· 1 shared C. S. Sorensen· 1 shared D. Dibitetto· 1 shared E. Gogola· 1 shared E. Rothenberg· 1 shared F. Vivalda· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

J. Jonkers

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2 papers

Recent·Most cited

Cancer BiologybioRxivMay 22, 2023

H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours

D. Dibitetto, M. Liptay, F. Vivalda…·S. Rottenberg

This study identifies H2AX's role in promoting replication fork degradation and chemosensitivity in BRCA-deficient tumours, independent of its classical DNA damage signalling function.

DOI 10.1038/s41467-024-48715-1

mouseDNA methylation

𝕏 PostBluesky

Cancer BiologybioRxivSep 25, 2019

PARPi synthetic lethality derives from replication-associated single-stranded DNA gaps

K. Cong, A. N. Kousholt, M. Peng…·S. Cantor

This study shows PARPi sensitivity in BRCA-deficient cells arises from replication-associated ssDNA gaps, not replication speed.

DOI 10.1016/j.molcel.2021.06.011

experimental assayhost-pathogen & immune response

𝕏 PostBluesky