BiophysicsbioRxiv
A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
S. Adams, A. G. Purkiss, P. P. Knowles…·N. Q. McDonald
The paper reports crystal and cryo-EM structures of zebrafish RET revealing conformational flexibility and strict geometric spacing in ligand-co-receptor recognition.
DOI 10.1016/j.str.2020.12.012