Reversible supramolecular assembly of the anti-microbial peptide plectasin into helical non-amyloid fibrils
C. Pohl, G. Effantin, E. Kandiah, S. Meier, G. Zeng, W. Streicher, G. H. Peters, G. Schoehn, C. Mueller-Dieckmann, A. Noergaard, P. Harris
The paper shows that a triple-mutant of plectasin forms reversible helical non-amyloid fibrils, with high-resolution structure and pH-dependent equilibrium.
bioRxiv · Sep 6, 2021 · PreprintBiophysics