Author

A. Osinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Organism:fungi (other)· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

V. S. Tagliabracci· 3 shared K. Pawlowski· 2 shared Y. Li· 2 shared Z. Chen· 2 shared A. Majumdar· 1 shared G. Hernandez· 1 shared G. J. Park· 1 shared J. Eitson· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiochemistry

V. S. Tagliabracci

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The mechanism of RNA capping by SARS-CoV-2

G. J. Park, A. Osinski, G. Hernandez, J. Eitson, A. Majumdar, M. Tonelli, K. Henzler-Wildman, K. Pawlowski, Z. Chen, Y. Li, J. Schoggins, V. S. Tagliabracci

This study reveals how SARS-CoV-2 caps its RNA genome through an unconventional mechanism involving RNAylation and methyltransferase activity, identifying potential antiviral targets.

bioRxiv · Feb 7, 2022Biochemistry

Structural and mechanistic basis for protein glutamylation by the kinase fold

A. Osinski, M. Black, K. Pawlowski, Z. Chen, Y. Li, V. S. Tagliabracci

This study reveals how the kinase fold of SidJ catalyzes protein glutamylation and identifies SdjA as a glutamylase regulating SidE-ligases during Legionella infection.

bioRxiv · Apr 13, 2021Biochemistry

A Legionella effector ADP-ribosyltransferase inactivates glutamate dehydrogenase

M. H. Black, A. Osinski, M. Gradowski, K. A. Servage, K. Pawłowski, V. S. Tagliabracci

This study identifies Lpg0181, a Legionella effector that inactivates host glutamate dehydrogenase, providing a novel mechanism for nutrient acquisition during infection.

bioRxiv · Aug 3, 2020Biochemistry