Author

A. Osswald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

S. Ocvirk· 2 shared A. Hamm· 1 shared A. J. Steelman· 1 shared A. M. Abdel-Hamid· 1 shared A. Schnieke· 1 shared B. Kleuser· 1 shared C. Greening· 1 shared C. Volet· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

S. Ocvirk

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Author profile →

2 papers

Recent·Most cited

Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer

E. Wortmann, A. Osswald, D. Wylensek, S. Kuhls, O. Coleman, Q. Ducarmon, W. Liang, N. Treichel, F. Schumacher, C. Volet, S. Matysik, K. Kleigrewe, M. Gigl, S. Rohn, B. Kleuser, , T. Clavel

The paper shows that secondary bile acids from gut bacteria worsen colorectal cancer in a Western diet model.

bioRxiv · Mar 17, 2023 · PreprintMicrobiology

Gut bacteria convert cortisol into a distinct hostsignalling molecule

M. Freiberg, T. Wang, R. S. d. L. Rosa, A. Osswald, M. C. R. Melo, D. G. Stouffer, P. S. Buobu, C. Welsh, L. Yang, A. M. Abdel-Hamid, H. L. Doden, S. Devendran, R. M. Pollet, S. Goldberg, L. Ray, , J. M. Ridlon

The paper shows gut bacteria convert cortisol into 20-dihydrocortisol, a distinct host signalling molecule that reprograms colonic transcription and activates inflammatory pathways via NR4A3.

bioRxiv · Jun 12, 2020 · PreprintMicrobiology