Cancer BiologybioRxiv
IER5, a DNA-damage response gene, is required for Notch-mediated induction of squamous cell differentiation
L. Pan, M. E. Lemieux, T. Thomas…·J. C. Aster
The paper identifies IER5 as a Notch-induced DNA-damage response gene required for squamous cell differentiation and shows its interaction with PP2A subunit PPP2R2A.
DOI 10.7554/elife.58081