Evolutionary BiologybioRxivPreprint
Structural adaptation of oxygen tolerance in 4-hydroxybutyrl-CoA dehydratase, a key enzyme of archaeal carbon fixation
H. DeMirci, B. Tolar, T. Doukov…·S. Wakatsuki
The paper investigates how 4HBD, a key enzyme in archaeal carbon fixation, adapted structurally to become oxygen-tolerant, revealing evolutionary changes that enabled aerobic metabolism.
DOI 10.1101/2020.02.05.935528