New role of cardiomyocyte Bmal1 in the regulation of sex-specific heart transcriptomes
X. Zhang, S. B. Procopio, H. Ding, M. G. Semel, E. A. Schroder, T. S. Seward, P. Du, K. K. Wu, S. R. Johnson, A. Prabhat, D. J. Schneider, I. G. Stumpf, E. R. Rozmus, Z. Huo, B. P. Delisle, K. A. Esser
This study shows that cardiomyocyte Bmal1 is essential for sex-specific gene expression in the adult mouse heart, as its loss reduces sex differences in circadian transcriptomes.
bioRxiv · Apr 18, 2024 · PreprintPhysiology