A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa
G. Neumayer, J. Torkelson, S. Li, K. McCarthy, H. Zhen, M. Vangipuram, J. Jackow, A. Rami, C. Hansen, Z. Guo, S. Gaddam, A. Pappalardo, L. Li, A. Cramer, K. Roy, , A. E. Oro
This paper develops a scalable, GMP-compatible cell therapy for Dystrophic Epidermolysis Bullosa using CRISPR-corrected iPS cells to generate functional skin grafts.
bioRxiv · Feb 28, 2023 · PreprintBioengineering