Author

A. Rosen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Casciola-Rosen· 2 shared A. A. Shah· 1 shared A. Baer· 1 shared A. Kau· 1 shared A. Rosenberg· 1 shared B. Antiochos· 1 shared C. Mecoli· 1 shared C. Tomera· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

L. Casciola-Rosen

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3 papers

Recent·Most cited

Secretory Leukocyte Protease Inhibitor Protects Against Severe Urinary Tract Infection in Mice

A. Rosen, M. Lint, D. Voelker, N. Gilbert, C. Tomera, J. Santiago Borges, M. A. Wallace, T. Hannan, C.-A. D. Burnham, S. Hultgren, A. Kau

This study shows that SLPI protects against acute UTI in mice and suggests SLPI is regulated in response to uropathogen exposure in women.

mBio · Feb 14, 2024Peer-reviewedImmunology

The DNA sensors AIM2 and IFI16 are NET-binding SLE autoantigens

B. Antiochos, P. Fenaroli, A. Rosenberg, A. Baer, J. Sohn, J. Li, M. Petri, D. W. Goldman, C. Mecoli, L. Casciola-Rosen, A. Rosen

The paper identifies AIM2 and IFI16 as autoantigens in SLE that bind NETs, leading to DNase-resistant structures that promote sustained IFN signaling.

bioRxiv · Aug 19, 2021Immunology

Estimating Autoantibody Signatures To Detect Autoimmune Disease Patient Subsets

Z. Wu, L. Casciola-Rosen, A. A. Shah, A. Rosen, S. L. Zeger

This paper develops a Bayesian hierarchical model to improve autoantibody signature detection by aligning and dewarping autoradiograms, enhancing subset identification in autoimmune diseases.

bioRxiv · Apr 21, 2017Immunology