Author

A. Rosowicz

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

A. M. Fundichely· 1 shared A. Polyzos· 1 shared C. J. Lee· 1 shared C. L. Liu· 1 shared C. S. Leslie· 1 shared D. Zheng· 1 shared E. Apostolou· 1 shared E. Khurana· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. M. Fundichely

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1 paper

Recent·Most cited

TAD hierarchy restricts poised LTR activation and loss of TAD hierarchy promotes LTR co-option in cancer

E. W. P. Wong, M. Sahin, R. Yang, U. Lee, Y. A. Zhan, R. Misra, F. Tomas, N. Alomran, A. Polyzos, C. J. Lee, T. Trieu, A. M. Fundichely, T. Wiesner, A. Rosowicz, S. Cheng, , P. Chi

The paper shows that TAD hierarchy restricts LTR activation, and its loss in cancer allows LTRs to act as alternative promoters, driving oncogene activation and transcriptional diversity.

bioRxiv · May 31, 2024 · PreprintCancer Biology