R. Misra

PRC2 Inactivating Mutations in Cancer are Synthetic Lethal with DNMT1 Targeted Therapy via Enhanced Viral Mimicry

This paper identifies synthetic lethality between PRC2 inactivation and DNMT1 inhibition in MPNST, showing enhanced cytotoxicity through retrotransposon activation and innate immune signaling.

Air pollution induces Staphylococcus aureus USA300 respiratory tract colonisation mediated by specific bacterial genetic responses dependent on the global virulence gene regulators Agr and Sae

This study shows that exposure to black carbon increases Staphylococcus aureus virulence and colonization by altering gene expression, independent of host factors.

Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

Roles of the EnvZ/OmpR Two-Component System and Porins in Iron Acquisition in Escherichia coli

This study shows that the EnvZ/OmpR system and porins enhance ferrous iron uptake in E. coli, overcoming Fur repression and resolving a paradox in iron regulon expression.