Author

A. S. George

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Organism:virus· 1

Frequent Co-Authors

A. J. Pruijssers· 2 shared D. P. Porter· 2 shared J. K. Perry· 2 shared L. J. Stevens· 2 shared M. R. Denison· 2 shared R. S. Baric· 2 shared T. Cihlar· 2 shared T. M. Hughes· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. J. Pruijssers

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 5, 2023

Evaluation Of Effect Of Bacteria On The Surface Of The Dental Implant

A. S. George, S. S, M. NP…·T. N

The study examines how bacteria affect the surface of dental implants using scanning electron microscopy and finds significant surface changes.

DOI 10.1101/2023.01.05.522965

imagingexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintJan 25, 2022

Distinct genetic determinants and mechanisms of SARS-CoV-2 resistance to remdesivir

L. J. Stevens, A. J. Pruijssers, H. W. Lee…·M. R. Denison

This study identifies distinct mutations in SARS-CoV-2's RdRp that confer remdesivir resistance, showing their biochemical mechanisms and transferability to other coronaviruses.

DOI 10.1101/2022.01.25.477724

viruswhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivApr 27, 2020

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.

A. J. Pruijssers, A. S. George, A. Schäfer…·T. P. Sheahan

This study shows remdesivir effectively inhibits SARS-CoV-2 in human cells and mice, reducing viral load and improving lung function.

DOI 10.1016/j.celrep.2020.107940

𝕏 PostBluesky