ImmunologybioRxiv
Allogeneic CAR-invariant Natural Killer T Cells Exert Potent Antitumor Effects Through Host CD8 T cell Cross-Priming
F. Simonetta, J. K. Lohmeyer, T. Hirai…·R. S. Negrin
This study shows allogeneic CAR-iNKT cells effectively combat tumors in mice by directly attacking cancer cells and boosting host CD8 T cell responses, even across major MHC barriers.
DOI 10.1158/1078-0432.ccr-21-1329