Author

J. K. Lohmeyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Baker· 3 shared R. S. Negrin· 3 shared F. Simonetta· 2 shared T. Hirai· 2 shared X. Ji· 2 shared A. Aalipour· 1 shared A. Bertaina· 1 shared A. Elezaby· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

J. Baker

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3 papers

Recent·Most cited

Extracellular release of damaged mitochondria induced by pre-hematopoietic stem cell transplant conditioning exacerbates graft-versus-host disease

V. Vijayan, H. Yan, J. K. Lohmeyer, K. A. Prentiss, R. V. Patil, G. Barbarito, I. Lopez, A. Elezaby, K. Peterson, J. Baker, N. P. Ostberg, A. Bertaina, R. S. Negrin, D. Mochly-Rosen, K. Weinberg, B. Haileselassie

This study shows that conditioning before hematopoietic stem cell transplant releases damaged mitochondria, which activate host APCs and worsen GVHD.

bioRxiv · Apr 24, 2023 · PreprintImmunology

Integrated Analysis of T cell Repertoire and Transcriptome Identifies Mechanisms of Regulatory T cell (Treg) Suppression of Acute Graft-versus-Host-Disease

J. K. Lohmeyer, T. Hirai, M. Turkoz, S. Buhler, T. L. Ramos, N. Koehler, J. Baker, X. Ji, J. Villard, Y. Chalandon, F. Simonetta, R. S. Negrin

This study identifies how regulatory T cells suppress acute graft-versus-host disease by modulating conventional T cell transcriptomes and metabolism without affecting graft-versus-tumor activity.

bioRxiv · Jul 26, 2022 · PreprintImmunology

Allogeneic CAR-invariant Natural Killer T Cells Exert Potent Antitumor Effects Through Host CD8 T cell Cross-Priming

F. Simonetta, J. K. Lohmeyer, T. Hirai, K. Maas-Bauer, M. Alvarez, A. S. Wenokur, J. Baker, A. Aalipour, X. Ji, S. Haile, C. L. Mackall, R. S. Negrin

This study shows allogeneic CAR-iNKT cells effectively combat tumors in mice by directly attacking cancer cells and boosting host CD8 T cell responses, even across major MHC barriers.

bioRxiv · Feb 3, 2021Immunology