Cancer BiologybioRxivPreprint
SOX2-phosphorylation toggles a bistable differentiation-switch in squamous cell carcinoma
S. Hoang-Phou, A. Sastre-Perona, M. Abbruzzese…·M. Schober
This paper identifies a mechanism by which SOX2-phosphorylation toggles a bistable differentiation switch in squamous cell carcinoma, enabling tumor-propagating cells to transition from self-renewal to differentiation.
DOI 10.1101/2021.08.18.455699