Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
S. Petroulia, K. Hockemeyer, S. Tiwari, P. Berico, S. Shamloo, S. E. Banijamali, E. Vega-Saenz de Miera, Y. Gong, P. Thandapani, E. Wang, M. Schulz, A. Tsirigos, I. Osman, I. Aifantis, J. Imig
The paper identifies lncRNAs involved in melanoma growth and metastasis using CRISPR-inhibition screens and validates their functional roles.
bioRxiv · Jul 24, 2024 · PreprintCancer Biology
D. Papaioannou, A. P. Urs, R. Buisson, A. Petri, R. Kulkarni, D. Nicolet, L. Woodward, C. Goda, K. Mrozek, G. K. Behbehani, S. Kauppinen, A.-K. Eisfeld, I. Aifantis, G. Singh, A. M. Dorrance, R. Garzon
This study identifies circPCMTD1 as a circular RNA that promotes leukemic cell proliferation by enhancing DNA damage response tolerance through a novel peptide product.
bioRxiv · Jun 27, 2024Cancer Biology
M. Guillamot, I. Subudhi, V. Paraskevopoulou, A. Prystupa, I. Sidhu, A. Yeaton, M. Laskou, C. Hannemann, C. Donahoe, D. Wiseman, I. Aifantis, S. Naik, A. Weinstock
This study shows that transient skin inflammation activates hematopoietic stem/progenitor cells via type I interferon, altering systemic immunity and affecting atherosclerosis and influenza outcomes.
bioRxiv · Apr 24, 2024Immunology
R. J. Austin, J. Straube, R. Halder, Y. Janardhanan, C. Bruedigam, M. Witkowski, L. Cooper, A. Porter, M. Braun, F. Souza-Fonseca-Guimaraes, S. A. Minnie, E. Cooper, S. Jacquelin, A. Song, T. Bald, , M. J. Bywater
This study shows that specific AML oncogenes influence immune responses and escape mechanisms, with NrasG12D promoting anti-leukemia immunity that can be counteracted by Myc.
bioRxiv · Feb 8, 2023Cancer Biology
R. Kedmi, T. Najar, K. R. Mesa, A. Grayson, L. Kroehling, Y. Hao, S. Hao, M. Pokrovskii, M. Xu, J. Talbot, J. Wang, J. Germino, C. A. Lareau, A. T. Satpathy, M. S. Anderson, , D. R. Littman
This study identifies a distinct RORγt+ antigen presenting cell subset that mediates microbiota-driven regulatory T cell differentiation, revealing a mechanism for maintaining immune tolerance.
bioRxiv · Nov 19, 2021 · PreprintImmunology
S. Hoang-Phou, A. Sastre-Perona, M. Abbruzzese, Z. Ying, J. Siegle, B. Aranda Orgilles, P. P. Rocha, I. Aifantis, J. Skok, S. Beronja, M. Schober
This paper identifies a mechanism by which SOX2-phosphorylation toggles a bistable differentiation switch in squamous cell carcinoma, enabling tumor-propagating cells to transition from self-renewal to differentiation.
bioRxiv · Aug 18, 2021 · PreprintCancer Biology
R. Kim, S. Nomikou, N. Coudray, G. Jour, Z. Dawood, R. Hong, E. Esteva, T. Sakellaropoulos, D. Donnelly, U. Moran, A. Hatzimemos, J. S. Weber, N. Razavian, I. Aifantis, D. Fenyo, , A. Tsirigos
This paper develops a deep learning model to detect BRAF mutations in melanoma histopathology images using whole slide images from 256 patients, achieving AUC scores of 0.96 and 0.72.
bioRxiv · Aug 19, 2020 · PreprintPathology
M. G. Noval, M. E. Kaczmarek, A. Koide, B. A. Rodriguez-Rodriguez, P. Louie, T. Tada, T. Hattori, T. Panchenko, L. A. Romero, K. W. Teng, A. Bazley, M. de Vries, M. I. Samanovic, J. N. Weiser, I. Aifantis, , K. A. Stapleford
The paper assesses neutralization capacity and antibody titers against SARS-CoV-2 antigens in recovered healthcare workers, finding that high titers of multiple isotypes correlate with neutralization.
bioRxiv · Aug 15, 2020 · PreprintMicrobiology
A. Kloetgen, P. Thandapani, P. Ntziachristos, Y. Ghebrechristos, S. Nomikou, C. Lazaris, X. Chen, H. Hu, S. Bakogianni, J. Wang, Y. Fu, F. Boccalatte, H. Zhong, E. Paietta, T. Trimarchi, , A. Tsirigos
The paper examines 3D chromatin changes in T-ALL, identifies TAD fusion events linked to oncogene activation, and shows drug treatments can restore some interactions.
bioRxiv · Aug 4, 2019Cancer Biology