Author

A. Sechi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Schalla· 3 shared M. Zenke· 2 shared A. E. I. Hamouda· 1 shared A. Paschen· 1 shared A. Roesch· 1 shared B. Shannan· 1 shared C. Krepler· 1 shared D. Picard· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

C. Schalla

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SPAG6 promotes cell migration and induces epithelial-to-mesenchymal transition in luminal breast cancer cells

J. Mijnes, S. Bringezu, J. Berger, C. Schalla, M. Rose, S. von Serenyi, R. Knuechel-Clarke, A. Sechi, E. Dahl

This study shows SPAG6 promotes migration and induces EMT in luminal breast cancer cells, with opposing effects based on molecular subtype.

bioRxiv · Mar 24, 2022 · PreprintCell Biology

Met-signaling controls Dendritic Cell migration by regulating podosome formation and function

A. E. I. Hamouda, C. Schalla, A. Sechi, M. Zenke, T. Hieronymus

This study shows Met-signaling regulates dendritic cell migration by controlling podosome formation and ECM degradation, with both HGF-dependent and -independent effects.

bioRxiv · Apr 28, 2021 · PreprintCell Biology

Persister state-directed transitioning and vulnerability in melanoma

H. Chauvistre, B. Shannan, S. M. Daignault, R. J. Ju, D. Picard, S. Egetemaier, R. Varaljai, A. Sechi, F. Kaschani, O. Keminer, S. J. Stehbens, Q. Liu, X. Yin, K. Jeyakumar, F. C. E. Vogel, , A. Roesch

This study identifies a compound that induces a persister state in melanoma cells, promoting differentiation and sensitizing them to a prodrug, offering a dual-target strategy for treatment.

bioRxiv · Apr 1, 2020Cancer Biology

LSP1-myosin1e bi-molecular complex regulates focal adhesion dynamics and cell migration

K. Schaeringer, S. Maxeiner, C. Schalla, S. Ruetten, M. Zenke, A. Sechi

This study shows that the LSP1-myosin1e complex regulates focal adhesion dynamics and cell migration in macrophages by controlling actin cytoskeleton remodeling.

bioRxiv · Feb 26, 2020Cell Biology