Author

A. Sharabi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

J. S. Gutkind· 2 shared R. Saddawi-Konefka· 2 shared V. H. Wu· 2 shared Z. Wang· 2 shared A. A. Molinolo· 1 shared A. B. Simon· 1 shared A. O'Farrell· 1 shared B. A. Fox· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

J. S. Gutkind

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2 papers

Recent·Most cited

Lymphatic-Preserving Treatment Sequencing with Immune Checkpoint Inhibition Unleashes cDC1-Dependent Antitumor Immunity in HNSCC

R. Saddawi-Konefka, A. O'Farrell, F. Faraji, L. Clubb, M. M. Allevato, N.-A. A. S. Anang, S. M. Jensen, Z. Wang, V. H. Wu, B. S. Yung, R. Al Msari, I. Franiak Pietryga, A. A. Molinolo, J. P. Mesirov, A. B. Simon, , J. S. Gutkind

This study shows that lymphatic-preserving treatment sequences enhance cDC1-dependent antitumor immunity in HNSCC by avoiding lymphablation, which compromises ICI response.

bioRxiv · Feb 1, 2022Cancer Biology

Microneedle-mediated intratumoral delivery of anti-CTLA-4 promotes cDC1-dependent eradication of oral squamous cell carcinoma with limited irAEs

M. Gilardi, R. Saddawi-Konefka, V. H. Wu, M. A. Lopez-Ramirez, Z. Wang, F. Soto, D. J. Steffen, M. Proietto, Z. Mikulski, H. Miki, A. Sharabi, D. Kupor, R. Rueda, D. P. Hollern, J. Wang, J. S. Gutkind

This study demonstrates that microneedle-mediated local delivery of anti-CTLA-4 antibody reduces immune-related adverse events while effectively treating oral squamous cell carcinoma.

bioRxiv · Dec 7, 2021Cancer Biology