Author

A. Sreekumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

D. W. B. Piyarathna· 3 shared J. A. Jones· 2 shared J. Gohlke· 2 shared N. Putluri· 2 shared U. Rasaily· 2 shared V. Putluri· 2 shared A. Balasubramanian· 1 shared A. Omilian· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

D. W. B. Piyarathna

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Author profile →

4 papers

Recent·Most cited

Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in Black American and White American patients with TNBC

Q. Zhu, A. Balasubramanian, J. R. Asirvatham, M. Chatterjee, D. W. B. Piyarathna, J. Kaur, N. Mohamed, L. Wu, S. Wang, N. Pourfarrokh, P. D. Binsol, M. Bhargava, U. Rasaily, Y. Xu, J. Zheng, , A. Sreekumar

This study uses spatial omics to identify distinct tumor microenvironment profiles in Black and White American TNBC patients, linking them to different immunosuppressive mechanisms and clinical outcomes.

bioRxiv · Mar 17, 2024Cancer Biology

Role of Adenosine Deaminase in Prostate Cancer Progression

C. Charles, S. M. Lloyd, D. W. B. Piyarathna, J. Gohlke, U. Rasaily, V. Putluri, B. W. Simons, A. Zaslavsky, S. Nallandhighal, N. Palanisamy, N. Navone, J. A. Jones, M. M. Ittmann, N. Putluri, D. R. Rowley, , A. Sreekumar

This study identifies adenosine deaminase (ADA) as a driver of prostate cancer progression and metastasis through metabolomics and in vitro/in vivo experiments.

bioRxiv · Aug 9, 2023 · PreprintCancer Biology

B3GALT6 Promotes Dormant Breast Cancer Cell Survival and Recurrence by Enabling Heparan Sulfate-Mediated FGF Signaling

A. Sreekumar, M. Lu, B. Choudhury, T.-c. Pan, D. K. Pant, C. J. Sterner, G. K. Belka, T. Toriumi, B. Benz, M. Escobar-Aguirre, F. E. Marino, J. D. Esko, L. A. Chodosh

The paper identifies B3GALT6 as a key regulator of dormant breast cancer cell survival and recurrence through heparan sulfate-mediated FGF signaling.

bioRxiv · Jan 31, 2023Cancer Biology

Lipid Alterations in African American Prostate Cancer

A. Ravindran, D. W. B. Piyarathna, J. Gohlke, V. Putluri, T. Soni, S. Lloyd, P. Castro, S. Pennathur, J. A. Jones, M. Ittmann, N. Putluri, G. Michailidis, T. Rajendiran, A. Sreekumar

The paper identifies lipid alterations associated with prostate cancer disparities in African American men through lipidomics profiling of tumor and benign tissues.

bioRxiv · Nov 5, 2021 · PreprintCancer Biology