M. Chatterjee

Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in Black American and White American patients with TNBC

This study uses spatial omics to identify distinct tumor microenvironment profiles in Black and White American TNBC patients, linking them to different immunosuppressive mechanisms and clinical outcomes.

mirror determines the far posterior domain in butterfly wings

This study identifies the transcription factor mirror as a selector gene responsible for defining the far posterior domain in butterfly wings, influencing wing shape, scale morphology, and color pattern.

Collagen receptor GPVI-mediated platelet activation and pro-coagulant activity aggravates inflammation and aortic wall remodelling in abdominal aortic aneurysm

This study shows that GPVI-mediated platelet activation worsens AAA by promoting inflammation and aortic wall remodeling, suggesting GPVI as a therapeutic target.

Chiral flows in the separating wall during cell division

The paper investigates chiral flows in the acto-myosin cortex during cell division in C. elegans embryos using PIV and hydrodynamic theory.

UVB modifies skin immune-stroma cross-talk and promotes effector T cell recruitment during cryptic Leishmania donovani infection

This study uses scRNA-seq and spatial transcriptomics to show UVB exposure alters immune-stromal interactions and T cell recruitment during cryptic Leishmania donovani infection.

Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

The paper shows that telomere length modulates IL1R1 expression via TRF2 binding, affecting immune signaling and macrophage infiltration in TNBC.

Glycosylated extracellular mucin domains protect against SARS CoV-2 infection at the respiratory surface

This study shows that glycosylated mucin domains on respiratory epithelial cells restrict SARS-CoV-2 infection by reducing viral entry.

Human Satellite III long non-coding RNA imparts survival benefits to cancer cells

This study shows that SatIII lncRNA promotes cancer cell survival by resisting chemotherapy and is induced in cancer cells independently of heat shock.

Early reduction in PD-L1 expression predicts faster treatment response in human cutaneous leishmaniasis

The paper identifies early reduction in PD-L1 expression as a predictor of faster treatment response to SSG in Sri Lankan cutaneous leishmaniasis patients.

Reproductive Isolation through Experimental Manipulation of Sexually Antagonistic Coevolution in Drosophila Melanogaster

This study shows that sexual conflict in Drosophila melanogaster leads to both premating and postmating reproductive isolation in allopatric populations.